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apalutamide will reduce the extent or impact of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP2C19 inducer, with medication which have been CYP2C19 substrates may end up in lower publicity to these remedies.Hyponatremia: Clinically significant hyponatrem

tecovirimat will improve the amount or outcome of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Monitor. Tecovirimat is often a weak inhibitor of CYP2C8 and CYP2C19. Monitor for adverse outcomes if coadministered with delicate substrates of such enzymes.butabarbital will lower the extent or result of diazepam by influencing h